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CD4 Regulates Susceptibility to Fas ligand– and Tumor Necrosis Factor–mediated Apoptosis
The current knowledge of CD4 function is limited to its role as a necessary coreceptor in TCR-initiated signaling. We have investigated whether CD4 regulates additional T cell functions. Using human primary resting CD4(+) T cells, we demonstrate that CD4 activation is sufficient to induce lymphocyte...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
1998
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212167/ https://www.ncbi.nlm.nih.gov/pubmed/9480981 |