Physical and Functional Association of the Major Histocompatibility Complex Class I Heavy Chain α3 Domain with the Transporter Associated with Antigen Processing

CD8(+) T lymphocytes recognize antigens as short, MHC class I-associated peptides derived by processing of cytoplasmic proteins. The transporter associated with antigen processing translocates peptides from the cytosol into the ER lumen, where they bind to the nascent class I molecules. To date, the...

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Detalles Bibliográficos
Autores principales: Kulig, Kimary, Nandi, Dipankar, Bacik, Igor, Monaco, John J., Vukmanovic, Stanislav
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
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Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212190/
https://www.ncbi.nlm.nih.gov/pubmed/9500789

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