Mucosal Adjuvanticity and Immunogenicity of LTR72, a Novel Mutant of Escherichia coli Heat-labile Enterotoxin with Partial Knockout of ADP-ribosyltransferase Activity

Heat-labile Escherichia coli enterotoxin (LT) has the innate property of being a strong mucosal immunogen and adjuvant. In the attempt to reduce toxicity and maintain the useful immunological properties, several LT mutants have been produced. Some of these are promising mucosal adjuvants. However, s...

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Detalles Bibliográficos
Autores principales: Giuliani, Marzia Monica, Del Giudice, Giuseppe, Giannelli, Valentina, Dougan, Gordon, Douce, Gill, Rappuoli, Rino, Pizza, Mariagrazia
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212201/
https://www.ncbi.nlm.nih.gov/pubmed/9529328

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