T Cell Development in Mice Lacking All T Cell Receptor ζ Family Members (ζ, η, and FcεRIγ)

The ζ family includes ζ, η, and FcεRIγ (Fcγ). Dimers of the ζ family proteins function as signal transducing subunits of the T cell antigen receptor (TCR), the pre-TCR, and a subset of Fc receptors. In mice lacking ζ/η chains, T cell development is impaired, yet low numbers of CD4(+) and CD8(+) T ce...

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Detalles Bibliográficos
Autores principales: Shores, Elizabeth W., Ono, Masao, Kawabe, Tsutomo, Sommers, Connie L., Tran, Tom, Lui, Kin, Udey, Mark C., Ravetch, Jeffrey, Love, Paul E.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212212/
https://www.ncbi.nlm.nih.gov/pubmed/9529325

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