T Cell–mediated Pathology in Two Models of Experimental Colitis Depends Predominantly on the Interleukin 12/Signal Transducer and Activator of Transcription (Stat)-4 Pathway, but Is Not Conditional on Interferon γ Expression by T Cells

The requirements for interleukin (IL)-12/signal transducer and activator of transcription (Stat)-4 signaling and induction of T cell–specific interferon (IFN)-γ expression in the development of T helper cell (Th)1–type pathology were examined in two different models of experimental colitis. In each...

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Detalles Bibliográficos
Autores principales: Simpson, Stephen J., Shah, Samir, Comiskey, Martina, de Jong, Ype P., Wang, Baoping, Mizoguchi, Emiko, Bhan, Atul K., Terhorst, Cox
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212228/
https://www.ncbi.nlm.nih.gov/pubmed/9547334

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