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A Double-Edged Kinase Lyn: A Positive and Negative Regulator for Antigen Receptor–mediated Signals

B cells from young lyn (−/−) mice are hyperresponsive to anti-IgM–induced proliferation, suggesting involvement of Lyn in negative regulation of B cell antigen receptor (BCR)-mediated signaling. Here we show that tyrosine phosphorylation of FcγRIIB and CD22 coreceptors, which are important for feedb...

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Detalles Bibliográficos
Autores principales:	Nishizumi, Hirofumi, Horikawa, Keisuke, Mlinaric-Rascan, Irena, Yamamoto, Tadashi
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 1998
Materias:	Brief Definitive Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212230/ https://www.ncbi.nlm.nih.gov/pubmed/9547345

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