Turnover of CD4(+) and CD8(+) T Lymphocytes in HIV-1 Infection as Measured by Ki-67 Antigen

We investigated CD4(+) and CD8(+) T cell turnover in both healthy and HIV-1–infected adults by measuring the nuclear antigen Ki-67 specific for cell proliferation. The mean growth fraction, corresponding to the expression of Ki-67, was 1.1% for CD4(+) T cells and 1.0% in CD8(+) T cells in healthy ad...

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Detalles Bibliográficos
Autores principales: Sachsenberg, Nicolas, Perelson, Alan S., Yerly, Sabine, Schockmel, Gérard A., Leduc, Dominique, Hirschel, Bernard, Perrin, Luc
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212238/
https://www.ncbi.nlm.nih.gov/pubmed/9547340

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