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Abrogation of Bronchial Eosinophilic Inflammation and Airway Hyperreactivity in Signal Transducers and Activators of Transcription (STAT)6-deficient Mice
Signal transducers and activators of transcription 6 (STAT6) is essential for interleukin 4–mediated responses, including class switching to IgE and induction of type 2 T helper cells. To investigate the role of STAT6 in allergic asthma in vivo, we developed a murine model of allergen-induced airway...
Autores principales: | Akimoto, Toshihiko, Numata, Fumio, Tamura, Misato, Takata, Yoshimi, Higashida, Noriko, Takashi, Tohru, Takeda, Kiyoshi, Akira, Shizuo |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1998
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212260/ https://www.ncbi.nlm.nih.gov/pubmed/9565645 |
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