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A Role for Fas in Negative Selection of Thymocytes In Vivo
To seek information on the role of Fas in negative selection, we examined subsets of thymocytes from normal neonatal mice versus Fas-deficient lpr/lpr mice injected with graded doses of antigen. In normal mice, injection of 1–100 μg of staphylococcal enterotoxin B (SEB) induced clonal elimination of...
Autores principales: | Kishimoto, Hidehiro, Surh, Charles D., Sprent, Jonathan |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1998
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212270/ https://www.ncbi.nlm.nih.gov/pubmed/9565635 |
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