Role of Dimerization of the Membrane-associated Growth Factor Kit Ligand in Juxtacrine Signaling: The Sl (17H) Mutation Affects Dimerization and Stability—Phenotypes in Hematopoiesis

The Kit ligand (KL)/Kit receptor pair functions in hematopoiesis, gametogenesis, and melanogenesis. KL is encoded at the murine steel (Sl) locus and encodes a membrane growth factor which may be proteolytically processed to produce soluble KL. The membrane-associated form of KL is critical in mediat...

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Detalles Bibliográficos
Autores principales: Tajima, Youichi, Huang, Eric J., Vosseller, Keith, Ono, Masao, Moore, Malcolm A.S., Besmer, Peter
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212272/
https://www.ncbi.nlm.nih.gov/pubmed/9565637

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212272/
https://www.ncbi.nlm.nih.gov/pubmed/9565637

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