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Sequence of the Spacer in the Recombination Signal Sequence Affects V(D)J Rearrangement Frequency and Correlates with Nonrandom Vκ Usage In Vivo

Functional variable (V), diversity (D), and joining (J) gene segments contribute unequally to the primary repertoire. One factor contributing to this nonrandom usage is the relative frequency with which the different gene segments rearrange. Variation from the consensus sequence in the heptamer and...

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Detalles Bibliográficos
Autores principales:	Nadel, Bertrand, Tang, Alan, Escuro, Guia, Lugo, Geanncarlo, Feeney, Ann J.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 1998
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212273/ https://www.ncbi.nlm.nih.gov/pubmed/9565641

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