CD4(+) T Cell Tolerance to Parenchymal Self-Antigens Requires Presentation by Bone Marrow–derived Antigen-presenting Cells

T cell tolerance to parenchymal self-antigens is thought to be induced by encounter of the T cell with its cognate peptide–major histocompatibility complex (MHC) ligand expressed on the parenchymal cell, which lacks appropriate costimulatory function. We have used a model system in which naive T cel...

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Detalles Bibliográficos
Autores principales: Adler, Adam J., Marsh, David W., Yochum, Gregory S., Guzzo, James L., Nigam, Ankesh, Nelson, William G., Pardoll, Drew M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212299/
https://www.ncbi.nlm.nih.gov/pubmed/9584134

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