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Eliminating a Region of Respiratory Syncytial Virus Attachment Protein Allows Induction of Protective Immunity without Vaccine-enhanced Lung Eosinophilia
In a murine model of respiratory syncytial virus disease, prior sensitization to the attachment glycoprotein (G) leads to pulmonary eosinophilia and enhanced illness. Three different approaches were taken to dissect the region of G responsible for enhanced disease and protection against challenge. F...
Autores principales: | Sparer, Tim E., Matthews, Stephen, Hussell, Tracy, Rae, Aaron J., Garcia-Barreno, Blanca, Melero, Jose A., Openshaw, Peter J.M. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1998
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212312/ https://www.ncbi.nlm.nih.gov/pubmed/9607931 |
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