Cargando…
Thalidomide Costimulates Primary Human T Lymphocytes, Preferentially Inducing Proliferation, Cytokine Production, and Cytotoxic Responses in the CD8+ Subset
The efficacy of thalidomide (α-phthalimido-glutarimide) therapy in leprosy patients with erythema nodosum leprosum is thought to be due to inhibition of tumor necrosis factor α. In other diseases reported to respond to thalidomide, the mechanism of action of the drug is unclear. We show that thalido...
Autores principales: | Haslett, Patrick A.J., Corral, Laura G., Albert, Matthew, Kaplan, Gilla |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1998
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212313/ https://www.ncbi.nlm.nih.gov/pubmed/9607928 |
Ejemplares similares
-
CD28 interaction with B7 costimulates primary allogeneic proliferative responses and cytotoxicity mediated by small, resting T lymphocytes
Publicado: (1992) -
CD28 Costimulation of T Helper 1 Cells Enhances Cytokine Release In Vivo
por: Langenhorst, Daniela, et al.
Publicado: (2018) -
Itk Negatively Regulates Induction of T Cell Proliferation by CD28 Costimulation
por: Liao, X. Charlene, et al.
Publicado: (1997) -
Thalidomide and Phosphodiesterase 4 Inhibitors as Host Directed Therapeutics for Tuberculous Meningitis: Insights From the Rabbit Model
por: Kumar, Ranjeet, et al.
Publicado: (2020) -
CD28, Costimulator or Agonist Receptor?
por: Margulies, David H.
Publicado: (2003)