The Role of Lymphocyte Subsets in Accelerated Diabetes in Nonobese Diabetic–Rat Insulin Promoter–B7-1 (NOD-RIP-B7-1) Mice

B7-1 transgene expression on the pancreatic islets in nonobese diabetic (NOD) mice leads to accelerated diabetes, with >50% of animals developing diabetes before 12 wk of age. The expression of B7-1 directly on the pancreatic β cells, which do not normally express costimulator molecules, converts...

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Detalles Bibliográficos
Autores principales: Susan Wong, F., Visintin, Irene, Wen, Li, Granata, Jennifer, Flavell, Richard, Janeway, Charles A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
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Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212360/
https://www.ncbi.nlm.nih.gov/pubmed/9625758

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