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Vav Regulates Peptide-specific Apoptosis in Thymocytes
The protooncogene Vav functions as a GDP/GTP exchange factor (GEF) for Rho-like small GTPases involved in cytoskeletal reorganization and cytokine production in T cells. Gene-targeted mice lacking Vav have a severe defect in positive and negative selection of T cell antigen receptor transgenic thymo...
Autores principales: | Kong, Young-Yun, Fischer, Klaus-Dieter, Bachmann, Martin F., Mariathasan, Sanjeev, Kozieradzki, Ivona, Nghiem, Mai P., Bouchard, Dennis, Bernstein, Alan, Ohashi, Pamela S., Penninger, Josef M. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1998
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212394/ https://www.ncbi.nlm.nih.gov/pubmed/9841924 |
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