Preselection Thymocytes Are More Sensitive to T Cell Receptor Stimulation Than Mature T Cells

During T cell development, thymocytes which are tolerant to self-peptides but reactive to foreign peptides are selected. The current model for thymocyte selection proposes that self-peptide–major histocompatibility complex (MHC) complexes that bind the T cell receptor with low affinity will promote...

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Detalles Bibliográficos
Autores principales: Davey, Gayle M., Schober, Sonya L., Endrizzi, Bart T., Dutcher, Angela K., Jameson, Stephen C., Hogquist, Kristin A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212399/
https://www.ncbi.nlm.nih.gov/pubmed/9815264

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