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Natural Killer (NK) Cell–mediated Cytotoxicity: Differential Use of TRAIL and Fas Ligand by Immature and Mature Primary Human NK Cells
Mature natural killer (NK) cells use Ca(2+)-dependent granule exocytosis and release of cytotoxic proteins, Fas ligand (FasL), and membrane-bound or secreted cytokines (tumor necrosis factor [TNF]-α) to induce target cell death. Fas belongs to the TNF receptor family of molecules, containing a conse...
Autores principales: | Zamai, Loris, Ahmad, Manzoor, Bennett, Ian M., Azzoni, Livio, Alnemri, Emad S., Perussia, Bice |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1998
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212426/ https://www.ncbi.nlm.nih.gov/pubmed/9858524 |
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