Immunization of Mice with Urease Vaccine Affords Protection against Helicobacter pylori Infection in the Absence of Antibodies and Is Mediated by MHC Class II–restricted Responses

We examined the roles of cell- and antibody-mediated immunity in urease vaccine–induced protection against Helicobacter pylori infection. Normal and knockout mice deficient in major histocompatibility complex (MHC) class I, MHC class II, or B cell responses were mucosally immunized with urease plus...

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Detalles Bibliográficos
Autores principales: Ermak, Thomas H., Giannasca, Paul J., Nichols, Richard, Myers, Gwendolyn A., Nedrud, John, Weltzin, Richard, Lee, Cynthia K., Kleanthous, Harold, Monath, Thomas P.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212427/
https://www.ncbi.nlm.nih.gov/pubmed/9858514

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