Interleukin 7 Receptor Control of  T Cell Receptor γ Gene Rearrangement: Role of Receptor-associated Chains and Locus Accessibility

VDJ recombination of T cell receptor and immunoglobulin loci occurs in immature lymphoid cells. Although the molecular mechanisms of DNA cleavage and ligation have become more clear, it is not understood what controls which target loci undergo rearrangement. In interleukin 7 receptor (IL-7R)α(−/−) m...

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Detalles Bibliográficos
Autores principales: Durum, Scott K., Candèias, Serge, Nakajima, Hiroshi, Leonard, Warren J., Baird, Allison M., Berg, Leslie J., Muegge, Kathrin
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212428/
https://www.ncbi.nlm.nih.gov/pubmed/9858510

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212428/
https://www.ncbi.nlm.nih.gov/pubmed/9858510

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