A Critical Role of Natural Immunoglobulin M in Immediate Defense Against Systemic Bacterial Infection

To evaluate the role of natural immunoglobulin (Ig)M in the immediate response against microbial infection, we tested mutant mice that are deficient in secreted (s)IgM in an acute peritonitis model induced by cecal ligation and puncture (CLP). 20% of wild-type mice died within 32 h of CLP, whereas 7...

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Detalles Bibliográficos
Autores principales: Boes, Marianne, Prodeus, Andrey P., Schmidt, Tara, Carroll, Michael C., Chen, Jianzhu
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Brief Definitive Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212438/
https://www.ncbi.nlm.nih.gov/pubmed/9858525

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212438/
https://www.ncbi.nlm.nih.gov/pubmed/9858525

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