Cerebral Ischemia Enhances Polyamine Oxidation: Identification of Enzymatically Formed 3-Aminopropanal as an Endogenous Mediator of Neuronal and Glial Cell Death

To elucidate endogenous mechanisms underlying cerebral damage during ischemia, brain polyamine oxidase activity was measured in rats subjected to permanent occlusion of the middle cerebral artery. Brain polyamine oxidase activity was increased significantly within 2 h after the onset of ischemia in...

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Detalles Bibliográficos
Autores principales: Ivanova, Svetlana, Botchkina, Galina I., Al-Abed, Yousef, Meistrell, Malcolm, Batliwalla, Franak, Dubinsky, Janet M., Iadecola, Constantino, Wang, Haichao, Gregersen, Peter K., Eaton, John W., Tracey, Kevin J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212443/
https://www.ncbi.nlm.nih.gov/pubmed/9670045

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