The Peripheral Deletion of Autoreactive CD8(+) T Cells Induced by Cross-presentation of Self-antigens Involves Signaling through CD95 (Fas, Apo-1)

Recently, we demonstrated that major histocompatibility complex class I–restricted cross-presentation of exogenous self-antigens can induce peripheral T cell tolerance by deletion of autoreactive CD8(+) T cells. In these studies, naive ovalbumin (OVA)-specific CD8(+) T cells from the transgenic line...

Descripción completa

Detalles Bibliográficos
Autores principales: Kurts, Christian, Heath, William R., Kosaka, Hiroshi, Miller, Jacques F.A.P., Carbone, Francis R.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Brief Definitive Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212451/
https://www.ncbi.nlm.nih.gov/pubmed/9670055

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212451/
https://www.ncbi.nlm.nih.gov/pubmed/9670055

Ejemplares similares