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The Peripheral Deletion of Autoreactive CD8(+) T Cells Induced by Cross-presentation of Self-antigens Involves Signaling through CD95 (Fas, Apo-1)
Recently, we demonstrated that major histocompatibility complex class I–restricted cross-presentation of exogenous self-antigens can induce peripheral T cell tolerance by deletion of autoreactive CD8(+) T cells. In these studies, naive ovalbumin (OVA)-specific CD8(+) T cells from the transgenic line...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
1998
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212451/ https://www.ncbi.nlm.nih.gov/pubmed/9670055 |