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Cytotoxic T Lymphocyte Antigen 4 Is Induced in the Thymus upon In Vivo Activation and Its Blockade Prevents Anti-CD3–mediated Depletion of Thymocytes

The development of a normal T cell repertoire in the thymus is dependent on the interplay between signals mediating cell survival (positive selection) and cell death (negative selection or death by neglect). Although the CD28 costimulatory molecule has been implicated in this process, it has been di...

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Detalles Bibliográficos
Autores principales:	Cilio, Corrado M., Daws, Michael R., Malashicheva, Anna, Sentman, Charles L., Holmberg, Dan
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 1998
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212496/ https://www.ncbi.nlm.nih.gov/pubmed/9763603

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