Ex Vivo Staining of Metastatic Lymph Nodes by Class I Major Histocompatibility Complex Tetramers Reveals High Numbers of Antigen-experienced Tumor-specific Cytolytic T Lymphocytes

Characterization of cytolytic T lymphocyte (CTL) responses to tumor antigens has been impeded by a lack of direct assays of CTL activity. We have synthesized reagents (“tetramers”) that specifically stain CTLs recognizing melanoma antigens. Tetramer staining of tumor-infiltrated lymph nodes ex vivo...

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Detalles Bibliográficos
Autores principales: Romero, Pedro, Rod Dunbar, P., Valmori, Danila, Pittet, Mikaël, Ogg, Graham S., Rimoldi, Donata, Chen, Ji-Li, Liénard, Danielle, Cerottini, Jean-Charles, Cerundolo, Vincenzo
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
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Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212507/
https://www.ncbi.nlm.nih.gov/pubmed/9802976

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