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Microarray gene expression profiling of osteoarthritic bone suggests altered bone remodelling, WNT and transforming growth factor-β/bone morphogenic protein signalling

Osteoarthritis (OA) is characterized by alterations to subchondral bone as well as articular cartilage. Changes to bone in OA have also been identified at sites distal to the affected joint, which include increased bone volume fraction and reduced bone mineralization. Altered bone remodelling has be...

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Detalles Bibliográficos
Autores principales: Hopwood, Blair, Tsykin, Anna, Findlay, David M, Fazzalari, Nicola L
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212557/
https://www.ncbi.nlm.nih.gov/pubmed/17900349
http://dx.doi.org/10.1186/ar2301