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Microarray gene expression profiling of osteoarthritic bone suggests altered bone remodelling, WNT and transforming growth factor-β/bone morphogenic protein signalling
Osteoarthritis (OA) is characterized by alterations to subchondral bone as well as articular cartilage. Changes to bone in OA have also been identified at sites distal to the affected joint, which include increased bone volume fraction and reduced bone mineralization. Altered bone remodelling has be...
Autores principales: | Hopwood, Blair, Tsykin, Anna, Findlay, David M, Fazzalari, Nicola L |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212557/ https://www.ncbi.nlm.nih.gov/pubmed/17900349 http://dx.doi.org/10.1186/ar2301 |
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