Elevated extracellular matrix production and degradation upon bone morphogenetic protein-2 (BMP-2) stimulation point toward a role for BMP-2 in cartilage repair and remodeling

Bone morphogenetic protein-2 (BMP-2) has been proposed as a tool for cartilage repair and as a stimulant of chondrogenesis. In healthy cartilage, BMP-2 is hardly present, whereas it is highly expressed during osteoarthritis. To assess its function in cartilage, BMP-2 was overexpressed in healthy mur...

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Detalles Bibliográficos
Autores principales: Davidson, Esmeralda N Blaney, Vitters, Elly L, van Lent, Peter LEM, van de Loo, Fons AJ, van den Berg, Wim B, van der Kraan, Peter M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212581/
https://www.ncbi.nlm.nih.gov/pubmed/17922907
http://dx.doi.org/10.1186/ar2305

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212581/
https://www.ncbi.nlm.nih.gov/pubmed/17922907
http://dx.doi.org/10.1186/ar2305

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