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Production of single chain Fab (scFab) fragments in Bacillus megaterium

BACKGROUND: The demand on antigen binding reagents in research, diagnostics and therapy raises questions for novel antibody formats as well as appropriate production systems. Recently, the novel single chain Fab (scFab) antibody format combining properties of single chain Fv (scFv) and Fab fragments...

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Detalles Bibliográficos
Autores principales: Jordan, Eva, Al-Halabi, Laila, Schirrmann, Thomas, Hust, Michael, Dübel, Stefan
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212634/
https://www.ncbi.nlm.nih.gov/pubmed/18042285
http://dx.doi.org/10.1186/1475-2859-6-38