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Production of single chain Fab (scFab) fragments in Bacillus megaterium
BACKGROUND: The demand on antigen binding reagents in research, diagnostics and therapy raises questions for novel antibody formats as well as appropriate production systems. Recently, the novel single chain Fab (scFab) antibody format combining properties of single chain Fv (scFv) and Fab fragments...
Autores principales: | Jordan, Eva, Al-Halabi, Laila, Schirrmann, Thomas, Hust, Michael, Dübel, Stefan |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212634/ https://www.ncbi.nlm.nih.gov/pubmed/18042285 http://dx.doi.org/10.1186/1475-2859-6-38 |
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