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Detection of short repeated genomic sequences on metaphase chromosomes using padlock probes and target primed rolling circle DNA synthesis

BACKGROUND: In situ detection of short sequence elements in genomic DNA requires short probes with high molecular resolution and powerful specific signal amplification. Padlock probes can differentiate single base variations. Ligated padlock probes can be amplified in situ by rolling circle DNA synt...

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Detalles Bibliográficos
Autores principales:	Lohmann, Jakob S, Stougaard, Magnus, Koch, Jørn
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2007
Materias:	Methodology Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212658/ https://www.ncbi.nlm.nih.gov/pubmed/17997865 http://dx.doi.org/10.1186/1471-2199-8-103

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