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A B Cell Receptor with Two Igα Cytoplasmic Domains Supports Development of Mature But Anergic B Cells
B cell receptor (BCR) signaling is mediated through immunoglobulin (Ig)α and Igβ a membrane-bound heterodimer. Igα and Igβ are redundant in their ability to support early B cell development, but their roles in mature B cells have not been defined. To examine the function of Igα–Igβ in mature B cells...
Autores principales: | Reichlin, Amy, Gazumyan, Anna, Nagaoka, Hitoshi, Kirsch, Kathrin H., Kraus, Manfred, Rajewsky, Klaus, Nussenzweig, Michel C. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212724/ https://www.ncbi.nlm.nih.gov/pubmed/15024049 http://dx.doi.org/10.1084/jem.20031140 |
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