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CD152 (CTLA-4) Determines the Unequal Resistance of Th1 and Th2 Cells against Activation-induced Cell Death by a Mechanism Requiring PI3 Kinase Function

Survival of antigen-experienced T cells is essential for the generation of adaptive immune responses. Here, we show that the genetic and antibody-mediated inactivation of CD152 (cytotoxic T lymphocyte antigen 4) in T helper (Th) effector cells reduced the frequency of nonapoptotic cells in a complet...

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Detalles Bibliográficos
Autores principales:	Pandiyan, Pushpa, Gärtner, Dagmar, Soezeri, Osman, Radbruch, Andreas, Schulze-Osthoff, Klaus, Brunner-Weinzierl, Monika C.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2004
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212725/ https://www.ncbi.nlm.nih.gov/pubmed/15007096 http://dx.doi.org/10.1084/jem.20031058

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