Senescent Impairment in Synergistic Cytokine Pathways That Provide Rapid Cardioprotection in the Rat Heart

Pretreatment of rodent hearts with platelet-derived growth factor (PDGF)–AB decreases myocardial injury after coronary occlusion. However, PDGF-AB cardioprotection is diminished in older animals, suggesting that downstream elements mediating and/or synergizing the actions of PDGF-AB may be limited i...

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Detalles Bibliográficos
Autores principales: Xaymardan, Munira, Zheng, Jingang, Duignan, Inga, Chin, Andrew, Holm, Jacquelyne M., Ballard, Victoria L.T., Edelberg, Jay M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212728/
https://www.ncbi.nlm.nih.gov/pubmed/15007092
http://dx.doi.org/10.1084/jem.20031639

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