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Constitutive Activation of STAT5A Promotes Human Hematopoietic Stem Cell Self-Renewal and Erythroid Differentiation

Activation of the transcription factor signal transducer and activator of transcription (STAT)5 is involved in various aspects of hematopoiesis, affecting cell proliferation, differentiation, and cell survival. Constitutive activation of STAT5 has also been associated with leukemic transformation. W...

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Detalles Bibliográficos
Autores principales: Schuringa, Jan Jacob, Chung, Ki Young, Morrone, Giovanni, Moore, Malcolm A.S.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212750/
https://www.ncbi.nlm.nih.gov/pubmed/15353555
http://dx.doi.org/10.1084/jem.20041024