Cargando…

Constitutive Activation of STAT5A Promotes Human Hematopoietic Stem Cell Self-Renewal and Erythroid Differentiation

Activation of the transcription factor signal transducer and activator of transcription (STAT)5 is involved in various aspects of hematopoiesis, affecting cell proliferation, differentiation, and cell survival. Constitutive activation of STAT5 has also been associated with leukemic transformation. W...

Descripción completa

Detalles Bibliográficos
Autores principales:	Schuringa, Jan Jacob, Chung, Ki Young, Morrone, Giovanni, Moore, Malcolm A.S.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2004
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212750/ https://www.ncbi.nlm.nih.gov/pubmed/15353555 http://dx.doi.org/10.1084/jem.20041024

Ejemplares similares

STAT5-mediated self-renewal of normal hematopoietic and leukemic stem cells
por: Schepers, Hein, et al.
Publicado: (2012)

Heterogeneity, Self-Renewal, and Differentiation of Hematopoietic Stem Cells
por: Jurecic, Roland, et al.
Publicado: (2012)

Gab2 Promotes Hematopoietic Stem Cell Maintenance and Self-Renewal Synergistically with STAT5
por: Li, Geqiang, et al.
Publicado: (2010)

Bmi-1 Regulates Extensive Erythroid Self-Renewal
por: Kim, Ah Ram, et al.
Publicado: (2015)

In Vitro Self-Renewal Division of Hematopoietic Stem Cells
por: Ema, Hideo, et al.
Publicado: (2000)

De novo DNA methyltransferase is essential for self-renewal, but not for differentiation, in hematopoietic stem cells
por: Tadokoro, Yuko, et al.
Publicado: (2007)

The transcription factor Zfp90 regulates the self-renewal and differentiation of hematopoietic stem cells
por: Liu, Ting, et al.
Publicado: (2018)

Smad4 is critical for self-renewal of hematopoietic stem cells
por: Karlsson, Göran, et al.
Publicado: (2007)

ZFP36L1 Negatively Regulates Erythroid Differentiation of CD34+ Hematopoietic Stem Cells by Interfering with the Stat5b Pathway
por: Vignudelli, Tatiana, et al.
Publicado: (2010)

Roles of Retinoids and Retinoic Acid Receptors in the Regulation of Hematopoietic Stem Cell Self-Renewal and Differentiation
por: E. Purton, Louise
Publicado: (2007)

Requirements for survivin in terminal differentiation of erythroid cells and maintenance of hematopoietic stem and progenitor cells
por: Leung, Cindy G., et al.
Publicado: (2007)

PPARα and glucocorticoid receptor synergize to promote erythroid progenitor self-renewal
por: Lee, Hsiang-Ying, et al.
Publicado: (2015)

Constitutive Activation of the Canonical NF-κB Pathway Leads to Bone Marrow Failure and Induction of Erythroid Signature in Hematopoietic Stem Cells
por: Nakagawa, Masahiro Marshall, et al.
Publicado: (2018)

Smurf2 regulates hematopoietic stem cell self-renewal and aging
por: Ramkumar, Charusheila, et al.
Publicado: (2014)

RARγ is critical for maintaining a balance between hematopoietic stem cell self-renewal and differentiation
por: Purton, Louise E., et al.
Publicado: (2006)

Satb1 regulates hematopoietic stem cell self-renewal by promoting quiescence and repressing differentiation commitment
por: Will, Britta, et al.
Publicado: (2013)

LIGHT/LTβR signaling regulates self-renewal and differentiation of hematopoietic and leukemia stem cells
por: Höpner, S. S., et al.
Publicado: (2021)

Regulation of hematopoietic stem cells differentiation, self-renewal, and quiescence through the mTOR signaling pathway
por: Ling, Bai, et al.
Publicado: (2023)

Role of YAP in hematopoietic differentiation and erythroid lineage specification of human-induced pluripotent stem cells
por: Laowtammathron, Chuti, et al.
Publicado: (2023)

Loss of IKKβ but Not NF-κB p65 Skews Differentiation towards Myeloid over Erythroid Commitment and Increases Myeloid Progenitor Self-Renewal and Functional Long-Term Hematopoietic Stem Cells
por: Zhang, Jing, et al.
Publicado: (2015)

Nuclear Factor Erythroid 2 Regulates Human HSC Self-Renewal and T Cell Differentiation by Preventing NOTCH1 Activation
por: Di Tullio, Alessandro, et al.
Publicado: (2017)

GATA-3 REGULATES THE SELF-RENEWAL OF LONG-TERM HEMATOPOIETIC STEM CELLS
por: Frelin, Catherine, et al.
Publicado: (2013)

Modest Declines in Proteome Quality Impair Hematopoietic Stem Cell Self-Renewal
por: Jose, Lorena Hidalgo San, et al.
Publicado: (2020)

The Hematopoietic Oxidase NOX2 Regulates Self-Renewal of Leukemic Stem Cells
por: Adane, Biniam, et al.
Publicado: (2019)

BMP signaling is required for postnatal murine hematopoietic stem cell self-renewal
por: Warsi, Sarah, et al.
Publicado: (2020)

Hematopoietic Stem Cell Factors: Their Functional Role in Self-Renewal and Clinical Aspects
por: Mann, Zoya, et al.
Publicado: (2022)

Tet2 disruption leads to enhanced self-renewal and altered differentiation of fetal liver hematopoietic stem cells
por: Kunimoto, Hiroyoshi, et al.
Publicado: (2012)

Zfp36l2 is required for self-renewal of early erythroid BFU-E progenitors
por: Zhang, Lingbo, et al.
Publicado: (2013)

Thioredoxin-1 regulates self-renewal and differentiation of murine hematopoietic stem cells through p53 tumor suppressor
por: Jabbar, Shaima, et al.
Publicado: (2022)

R274X-mutated Phf6 increased the self-renewal and skewed T cell differentiation of hematopoietic stem cells
por: Lan, Yanjie, et al.
Publicado: (2023)

Loss of quiescence and self-renewal capacity of hematopoietic stem cell in an in vitro leukemic niche
por: Vanegas, Natalia-Del Pilar, et al.
Publicado: (2017)

GRK6 regulates ROS response and maintains hematopoietic stem cell self-renewal
por: Le, Qiumin, et al.
Publicado: (2016)

Using Zebrafish to Study Pathways that Regulate Hematopoietic Stem Cell Self-Renewal and Migration
por: Choudhuri, Avik, et al.
Publicado: (2017)

miR-99 regulates normal and malignant hematopoietic stem cell self-renewal
por: Khalaj, Mona, et al.
Publicado: (2017)

Glutamylation of deubiquitinase BAP1 controls self-renewal of hematopoietic stem cells and hematopoiesis
por: Xiong, Zhen, et al.
Publicado: (2019)

Antioxidant Small Molecule Compound Chrysin Promotes the Self-Renewal of Hematopoietic Stem Cells
por: Li, Yinghui, et al.
Publicado: (2020)

Interleukin-12 supports in vitro self-renewal of long-term hematopoietic stem cells
por: Zhang, Shanshan, et al.
Publicado: (2019)

Micro‐RNAs: A safety net to protect hematopoietic stem cell self‐renewal
por: Crisafulli, Laura, et al.
Publicado: (2021)

Alkbh5 plays indispensable roles in maintaining self-renewal of hematopoietic stem cells
por: Yang, Bijie, et al.
Publicado: (2023)

Convergence of Hypoxia and TGFβ Pathways on Cell Cycle Regulation in Human Hematopoietic Stem/Progenitor Cells
por: Wierenga, Albertus T. J., et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_59v39tqp86usbgei7vt3i0u11g