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TACI and BAFF-R mediate isotype switching in B cells

The tumor necrosis factor family members BAFF and APRIL induce Ig isotype switching in human B cells. We analyzed the ability of BAFF and APRIL to induce isotype switching in murine B cells to IgG1, IgA, and IgE. APRIL and BAFF each engage two receptors, transmembrane activator and calcium-modulator...

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Detalles Bibliográficos
Autores principales:	Castigli, Emanuela, Wilson, Stephen A., Scott, Sumi, Dedeoglu, Fatma, Xu, Shengli, Lam, Kong-Peng, Bram, Richard J., Jabara, Haifa, Geha, Raif S.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2005
Materias:	Brief Definitive Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212754/ https://www.ncbi.nlm.nih.gov/pubmed/15630136 http://dx.doi.org/10.1084/jem.20032000

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