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Hypoxia-induced neutrophil survival is mediated by HIF-1α–dependent NF-κB activity
Neutrophils are key effector cells of the innate immune response and are required to migrate and function within adverse microenvironmental conditions. These inflammatory sites are characterized by low levels of oxygen and glucose and high levels of reductive metabolites. A major regulator of neutro...
Autores principales: | Walmsley, Sarah R., Print, Cristin, Farahi, Neda, Peyssonnaux, Carole, Johnson, Randall S., Cramer, Thorsten, Sobolewski, Anastasia, Condliffe, Alison M., Cowburn, Andrew S., Johnson, Nicola, Chilvers, Edwin R. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212759/ https://www.ncbi.nlm.nih.gov/pubmed/15630139 http://dx.doi.org/10.1084/jem.20040624 |
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