Role of β2-integrins for homing and neovascularization capacity of endothelial progenitor cells

The mechanisms of homing of endothelial progenitor cells (EPCs) to sites of ischemia are unclear. Here, we demonstrate that ex vivo–expanded EPCs as well as murine hematopoietic Sca-1(+)/Lin(−) progenitor cells express β2-integrins, which mediate the adhesion of EPCs to endothelial cell monolayers a...

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Detalles Bibliográficos
Autores principales: Chavakis, Emmanouil, Aicher, Alexandra, Heeschen, Christopher, Sasaki, Ken-ichiro, Kaiser, Ralf, El Makhfi, Naual, Urbich, Carmen, Peters, Thorsten, Scharffetter-Kochanek, Karin, Zeiher, Andreas M., Chavakis, Triantafyllos, Dimmeler, Stefanie
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212777/
https://www.ncbi.nlm.nih.gov/pubmed/15623573
http://dx.doi.org/10.1084/jem.20041402

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