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Prevention of UV radiation–induced immunosuppression by IL-12 is dependent on DNA repair

The immunostimulatory cytokine IL-12 is able to antagonize immunosuppression induced by solar/ultraviolet (UV) radiation via yet unknown mechanisms. IL-12 was recently found to induce deoxyribonucleic acid (DNA) repair. UV-induced DNA damage is an important molecular trigger for UV-mediated immunosu...

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Detalles Bibliográficos
Autores principales:	Schwarz, Agatha, Maeda, Akira, Kernebeck, Kerstin, van Steeg, Harry, Beissert, Stefan, Schwarz, Thomas
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2005
Materias:	Brief Definitive Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212783/ https://www.ncbi.nlm.nih.gov/pubmed/15657287 http://dx.doi.org/10.1084/jem.20041212

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