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BAFF is produced by astrocytes and up-regulated in multiple sclerosis lesions and primary central nervous system lymphoma
We report that B cell–activating factor of the tumor necrosis factor (TNF) family (BAFF) is expressed in the normal human brain at ∼10% of that in lymphatic tissues (tonsils and adenoids) and is produced by astrocytes. BAFF was regularly detected by enzyme-linked immunosorbent assay in brain tissue...
Autores principales: | Krumbholz, Markus, Theil, Diethilde, Derfuss, Tobias, Rosenwald, Andreas, Schrader, Frank, Monoranu, Camelia-Maria, Kalled, Susan L., Hess, Donna M., Serafini, Barbara, Aloisi, Francesca, Wekerle, Hartmut, Hohlfeld, Reinhard, Meinl, Edgar |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212784/ https://www.ncbi.nlm.nih.gov/pubmed/15642740 http://dx.doi.org/10.1084/jem.20041674 |
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