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Cotranslational endoplasmic reticulum assembly of FcɛRI controls the formation of functional IgE-binding receptors
The human high affinity receptor for IgE (FcɛRI) is a cell surface structure critical for the pathology of allergic reactions. Human FcɛRI is expressed as a tetramer (αβγ(2)) on basophils or mast cells and as trimeric (αγ(2)) complex on antigen-presenting cells. Expression of the human α subunit can...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2005
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212795/ https://www.ncbi.nlm.nih.gov/pubmed/15642744 http://dx.doi.org/10.1084/jem.20041384 |