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Contrasting frequencies of antitumor and anti-vaccine T cells in metastases of a melanoma patient vaccinated with a MAGE tumor antigen

Melanoma patients have high frequencies of T cells directed against antigens of their tumor. The frequency of these antitumor T cells in the blood is usually well above that of the anti-vaccine T cells observed after vaccination with tumor antigens. In a patient vaccinated with a MAGE-3 antigen pres...

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Detalles Bibliográficos
Autores principales: Lurquin, Christophe, Lethé, Bernard, De Plaen, Etienne, Corbière, Véronique, Théate, Ivan, van Baren, Nicolas, Coulie, Pierre G., Boon, Thierry
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212799/
https://www.ncbi.nlm.nih.gov/pubmed/15657294
http://dx.doi.org/10.1084/jem.20041378