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Cyclical modulation of sphingosine-1-phosphate receptor 1 surface expression during lymphocyte recirculation and relationship to lymphoid organ transit

Sphingosine-1-phosphate receptor 1 (S1P(1)) was recently shown to be required for lymphocyte egress from lymphoid organs. Here we have examined the relationship between S1P(1) abundance on the cell and egress efficiency. Using an integrin neutralization approach to separate the processes of entry an...

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Detalles Bibliográficos
Autores principales: Lo, Charles G., Xu, Ying, Proia, Richard L., Cyster, Jason G.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212802/
https://www.ncbi.nlm.nih.gov/pubmed/15657295
http://dx.doi.org/10.1084/jem.20041509