The Innate Mononuclear Phagocyte Network Depletes B Lymphocytes through Fc Receptor–dependent Mechanisms during Anti-CD20 Antibody Immunotherapy

Anti-CD20 antibody immunotherapy effectively treats non-Hodgkin's lymphoma and autoimmune disease. However, the cellular and molecular pathways for B cell depletion remain undefined because human mechanistic studies are limited. Proposed mechanisms include antibody-, effector cell–, and complem...

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Detalles Bibliográficos
Autores principales: Uchida, Junji, Hamaguchi, Yasuhito, Oliver, Julie A., Ravetch, Jeffrey V., Poe, Jonathan C., Haas, Karen M., Tedder, Thomas F.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212805/
https://www.ncbi.nlm.nih.gov/pubmed/15210744
http://dx.doi.org/10.1084/jem.20040119

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