Cargando…

The Roles of Two IκB Kinase-related Kinases in Lipopolysaccharide and Double Stranded RNA Signaling and Viral Infection

Viral infection and stimulation with lipopolysaccharide (LPS) or double stranded RNA (dsRNA) induce phosphorylation of interferon (IFN) regulatory factor (IRF)-3 and its translocation to the nucleus, thereby leading to the IFN-β gene induction. Recently, two IκB kinase (IKK)–related kinases, inducib...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hemmi, Hiroaki, Takeuchi, Osamu, Sato, Shintaro, Yamamoto, Masahiro, Kaisho, Tsuneyasu, Sanjo, Hideki, Kawai, Taro, Hoshino, Katsuaki, Takeda, Kiyoshi, Akira, Shizuo
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2004
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212809/ https://www.ncbi.nlm.nih.gov/pubmed/15210742 http://dx.doi.org/10.1084/jem.20040520

Ejemplares similares

Iκb Kinase α Is Essential for Mature B Cell Development and Function
por: Kaisho, Tsuneyasu, et al.
Publicado: (2001)

Essential Role of Nuclear Factor (NF)-κB–Inducing Kinase and Inhibitor of κb (Iκb) Kinase α in Nf-κb Activation through Lymphotoxin β Receptor, but Not through Tumor Necrosis Factor Receptor I
por: Matsushima, Akemi, et al.
Publicado: (2001)

Impairment of Natural Killer Cytotoxic Activity and Interferon γ Production in Ccaat/Enhancer Binding Protein γ–Deficient Mice
por: Kaisho, Tsuneyasu, et al.
Publicado: (1999)

Inhibitor of IκB kinase activity, BAY 11-7082, interferes with interferon regulatory factor 7 nuclear translocation and type I interferon production by plasmacytoid dendritic cells
por: Miyamoto, Rie, et al.
Publicado: (2010)

Crucial roles of XCR1-expressing dendritic cells and the XCR1-XCL1 chemokine axis in intestinal immune homeostasis
por: Ohta, Tomokazu, et al.
Publicado: (2016)

Interferon-α and Interleukin-12 Are Induced Differentially by Toll-like Receptor 7 Ligands in Human Blood Dendritic Cell Subsets
por: Ito, Tomoki, et al.
Publicado: (2002)

Toll-like receptor 9 mediates innate immune activation by the malaria pigment hemozoin
por: Coban, Cevayir, et al.
Publicado: (2005)

PDLIM1 inhibits NF-κB-mediated inflammatory signaling by sequestering the p65 subunit of NF-κB in the cytoplasm
por: Ono, Rumiko, et al.
Publicado: (2015)

Interleukin-1 receptor-associated kinase-1 plays an essential role for Toll-like receptor (TLR)7- and TLR9-mediated interferon-α induction
por: Uematsu, Satoshi, et al.
Publicado: (2005)

Conventional Type 1 Dendritic Cells in Intestinal Immune Homeostasis
por: Sasaki, Izumi, et al.
Publicado: (2022)

Cholera toxin B induces interleukin-1β production from resident peritoneal macrophages through the pyrin inflammasome as well as the NLRP3 inflammasome
por: Orimo, Takashi, et al.
Publicado: (2019)

SpiB regulates the expression of B-cell-related genes and increases the longevity of memory B cells
por: Horiuchi, Shu, et al.
Publicado: (2023)

Enhanced TLR-mediated NF-IL6–dependent gene expression by Trib1 deficiency
por: Yamamoto, Masahiro, et al.
Publicado: (2007)

Essential role of IRAK-4 protein and its kinase activity in Toll-like receptor–mediated immune responses but not in TCR signaling
por: Kawagoe, Tatsukata, et al.
Publicado: (2007)

Essential involvement of the CX3CL1-CX3CR1 axis in bleomycin-induced pulmonary fibrosis via regulation of fibrocyte and M2 macrophage migration
por: Ishida, Yuko, et al.
Publicado: (2017)

Immune Cell Activation by Bacterial Cpg-DNA through Myeloid Differentiation Marker 88 and Tumor Necrosis Factor Receptor–Associated Factor (Traf)6
por: Häcker, Hans, et al.
Publicado: (2000)

PDLIM7 Synergizes With PDLIM2 and p62/Sqstm1 to Inhibit Inflammatory Signaling by Promoting Degradation of the p65 Subunit of NF-κB
por: Jodo, Aya, et al.
Publicado: (2020)

Tmem45b is essential for inflammation- and tissue injury–induced mechanical pain hypersensitivity
por: Tanioku, Tadashi, et al.
Publicado: (2022)

Heme ameliorates dextran sodium sulfate-induced colitis through providing intestinal macrophages with noninflammatory profiles
por: Kayama, Hisako, et al.
Publicado: (2018)

The Ets Transcription Factor Spi-B Is Essential for the Differentiation of Intestinal Microfold (M) Cells
por: Kanaya, Takashi, et al.
Publicado: (2012)

Limitation of immune tolerance–inducing thymic epithelial cell development by Spi-B–mediated negative feedback regulation
por: Akiyama, Nobuko, et al.
Publicado: (2014)

Essential role of IPS-1 in innate immune responses against RNA viruses
por: Kumar, Himanshu, et al.
Publicado: (2006)

Radiation inducible MafB gene is required for thymic regeneration
por: Hashimoto, Daiki, et al.
Publicado: (2021)

The Absence of Interleukin 1 Receptor–Related T1/St2 Does Not Affect T Helper Cell Type 2 Development and Its Effector Function
por: Hoshino, Katsuaki, et al.
Publicado: (1999)

Conditional Deletion of TAK1 in T Cells Reveals a Pivotal Role of TCRαβ(+) Intraepithelial Lymphocytes in Preventing Lymphopenia-Associated Colitis
por: Sanjo, Hideki, et al.
Publicado: (2015)

Length-dependent recognition of double-stranded ribonucleic acids by retinoic acid–inducible gene-I and melanoma differentiation–associated gene 5
por: Kato, Hiroki, et al.
Publicado: (2008)

A Lipopolysaccharide from Pantoea Agglomerans Is a Promising Adjuvant for Sublingual Vaccines to Induce Systemic and Mucosal Immune Responses in Mice via TLR4 Pathway
por: Fukasaka, Masahiro, et al.
Publicado: (2015)

Rab39a Interacts with Phosphatidylinositol 3-Kinase and Negatively Regulates Autophagy Induced by Lipopolysaccharide Stimulation in Macrophages
por: Seto, Shintaro, et al.
Publicado: (2013)

Role(s) of IL-2 inducible T cell kinase and Bruton's tyrosine kinase in mast cell response to lipopolysaccharide
por: Huang, Weishan, et al.
Publicado: (2016)

Immunogenic tumor cell death promotes dendritic cell migration and inhibits tumor growth via enhanced T cell immunity
por: Moriya, Taiki, et al.
Publicado: (2021)

Glycogen synthase kinase (GSK)-3 and the double-strand RNA-dependent kinase, PKR: When two kinases for the common good turn bad()
por: Piazzi, Manuela, et al.
Publicado: (2020)

Deconstructing IκB kinase
por: Van Epps, Heather L.
Publicado: (2005)

Toll-like receptor downstream signaling
por: Kawai, Taro, et al.
Publicado: (2005)

Regulation of innate immune signalling pathways by the tripartite motif (TRIM) family proteins
por: Kawai, Taro, et al.
Publicado: (2011)

TRAF6 Is Required for Generation of the B-1a B Cell Compartment as well as T Cell-Dependent and -Independent Humoral Immune Responses
por: Kobayashi, Takashi, et al.
Publicado: (2009)

MyD88 But Not TRIF Is Essential for Osteoclastogenesis Induced by Lipopolysaccharide, Diacyl Lipopeptide, and IL-1α
por: Sato, Nobuaki, et al.
Publicado: (2004)

Selective control of type I IFN induction by the Rac activator DOCK2 during TLR-mediated plasmacytoid dendritic cell activation
por: Gotoh, Kazuhito, et al.
Publicado: (2010)

Programmed cell death ligand 1 disruption by clustered regularly interspaced short palindromic repeats/Cas9‐genome editing promotes antitumor immunity and suppresses ovarian cancer progression
por: Yahata, Tamaki, et al.
Publicado: (2019)

Glycogen synthase kinase‐3β participates in acquired resistance to gemcitabine in pancreatic cancer
por: Uehara, Masahiro, et al.
Publicado: (2020)

Beta-Cryptoxanthin Inhibits Lipopolysaccharide-Induced Osteoclast Differentiation and Bone Resorption via the Suppression of Inhibitor of NF-κB Kinase Activity
por: Hirata, Narumi, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_lgr0v1ktjj1r9fppufq4b0l2dh