Cargando…

Toll-like Receptor 9–Dependent and –Independent Dendritic Cell Activation by Chromatin–Immunoglobulin G Complexes

Dendritic cell (DC) activation by nucleic acid–containing immunoglobulin (Ig)G complexes has been implicated in systemic lupus erythematosus (SLE) pathogenesis. However, the mechanisms responsible for activation and subsequent disease induction are not completely understood. Here we show that murine...

Descripción completa

Detalles Bibliográficos
Autores principales:	Boulé, Melissa W., Broughton, Courtney, Mackay, Fabienne, Akira, Shizuo, Marshak-Rothstein, Ann, Rifkin, Ian R.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2004
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212813/ https://www.ncbi.nlm.nih.gov/pubmed/15197227 http://dx.doi.org/10.1084/jem.20031942

Ejemplares similares

RNA-associated autoantigens activate B cells by combined B cell antigen receptor/Toll-like receptor 7 engagement
por: Lau, Christina M., et al.
Publicado: (2005)

Toll-like receptors in systemic autoimmune disease
por: Marshak-Rothstein, Ann
Publicado: (2006)

Toll-like receptors and innate immune responses in systemic lupus erythematosus
por: Lafyatis, Robert, et al.
Publicado: (2007)

Toll-like Receptor 9–mediated Recognition of Herpes Simplex Virus-2 by Plasmacytoid Dendritic Cells
por: Lund, Jennifer, et al.
Publicado: (2003)

Tolerant B Lymphocytes Acquire Resistance to Fas-mediated Apoptosis after Treatment with Interleukin 4 but Not after Treatment with Specific Antigen Unless a Surface Immunoglobulin Threshold Is Exceeded
por: Foote, Linda C., et al.
Publicado: (1998)

DNA-like class R inhibitory oligonucleotides (INH-ODNs) preferentially block autoantigen-induced B-cell and dendritic cell activation in vitro and autoantibody production in lupus-prone MRL-Fas(lpr/lpr )mice in vivo
por: Lenert, Petar, et al.
Publicado: (2009)

Toll-like receptor downstream signaling
por: Kawai, Taro, et al.
Publicado: (2005)

Interplay of Cyclic GMP-AMP Synthase/Stimulator of IFN Genes and Toll-Like Receptor Nucleic Acid Sensing Pathways in Autoinflammation and Abnormal Bone Formation due to DNaseII-Deficiency
por: Marshak-Rothstein, Ann, et al.
Publicado: (2020)

Toll-like receptor–independent gene induction program activated by mammalian DNA escaped from apoptotic DNA degradation
por: Okabe, Yasutaka, et al.
Publicado: (2005)

Toll-like receptor 9 controls anti-DNA autoantibody production in murine lupus
por: Christensen, Sean R., et al.
Publicado: (2005)

Interferon-α and Interleukin-12 Are Induced Differentially by Toll-like Receptor 7 Ligands in Human Blood Dendritic Cell Subsets
por: Ito, Tomoki, et al.
Publicado: (2002)

Ablation of Toll-like receptor 9 attenuates myocardial ischemia/reperfusion injury in mice
por: Kitazume-Taneike, Rika, et al.
Publicado: (2019)

Matrix Metalloprotease 9 Mediates Neutrophil Migration into the Airways in Response to Influenza Virus-Induced Toll-Like Receptor Signaling
por: Bradley, Linda M., et al.
Publicado: (2012)

Toll-like receptor 9 mediates innate immune activation by the malaria pigment hemozoin
por: Coban, Cevayir, et al.
Publicado: (2005)

Systems biology approaches to toll-like receptor signaling
por: Vandenbon, Alexis, et al.
Publicado: (2012)

NFATc1 Mediates Toll-Like Receptor-Independent Innate Immune Responses during Trypanosoma cruzi Infection
por: Kayama, Hisako, et al.
Publicado: (2009)

Disease in the Pld4(thss/thss) Model of Murine Lupus Requires TLR9
por: Gavin, Amanda L., et al.
Publicado: (2023)

Opposing Effects of Transmembrane and Soluble FAS Ligand Expression on Inflammation and Tumor Cell Survival
por: Hohlbaum, Andreas M., et al.
Publicado: (2000)

Properties regulating the nature of the plasmacytoid dendritic cell response to Toll-like receptor 9 activation
por: Guiducci, Cristiana, et al.
Publicado: (2006)

Identification of Toll-Like Receptor 9 as Parapoxvirus Ovis-Sensing Receptor in Plasmacytoid Dendritic Cells
por: von Buttlar, Heiner, et al.
Publicado: (2014)

Toll‐Like Receptor 9 Deficiency Breaks Tolerance to RNA‐Associated Antigens and Up‐Regulates Toll‐Like Receptor 7 Protein in Sle1 Mice
por: Celhar, Teja, et al.
Publicado: (2018)

CXCL14 Acts as a Specific Carrier of CpG DNA into Dendritic Cells and Activates Toll-like Receptor 9-mediated Adaptive Immunity
por: Tanegashima, Kosuke, et al.
Publicado: (2017)

Toll-like Receptor 9 Induced Dendritic Cell Activation Promotes Anti-Myeloperoxidase Autoimmunity and Glomerulonephritis
por: Ford, Sharon L., et al.
Publicado: (2023)

Collaborative Induction of Inflammatory Responses by Dectin-1 and Toll-like Receptor 2
por: Gantner, Benjamin N., et al.
Publicado: (2003)

Chromatin regulators shape the genotype–phenotype map
por: Landry, Christian R, et al.
Publicado: (2010)

Signaling Flux Redistribution at Toll-Like Receptor Pathway Junctions
por: Selvarajoo, Kumar, et al.
Publicado: (2008)

Role of Lactobacillus pentosus Strain b240 and the Toll-Like Receptor 2 Axis in Peyer's Patch Dendritic Cell-Mediated Immunoglobulin A Enhancement
por: Kotani, Yoshifumi, et al.
Publicado: (2014)

Toll-Like Receptor 9 Agonists for Cancer Therapy
por: Melisi, Davide, et al.
Publicado: (2014)

TANK is a negative regulator of Toll-like receptor signaling and critical for preventing autoimmune nephritis
por: Kawagoe, Tatsukata, et al.
Publicado: (2009)

IgD (+) age‐associated B cells are the progenitors of the main T‐independent B cell response to infection that generates protective Ab and can be induced by an inactivated vaccine in the aged
por: Kugler‐Umana, Olivia, et al.
Publicado: (2022)

The mechanisms of hydroxychloroquine in rheumatoid arthritis treatment: Inhibition of dendritic cell functions via Toll like receptor 9 signaling
por: Han, Jiaochan, et al.
Publicado: (2020)

Rapid CD4(+) T-cell responses to bacterial flagellin require dendritic cell expression of Syk and CARD9
por: Atif, Shaikh M, et al.
Publicado: (2015)

Interleukin-1 receptor-associated kinase-1 plays an essential role for Toll-like receptor (TLR)7- and TLR9-mediated interferon-α induction
por: Uematsu, Satoshi, et al.
Publicado: (2005)

Yellow fever vaccine YF-17D activates multiple dendritic cell subsets via TLR2, 7, 8, and 9 to stimulate polyvalent immunity
por: Querec, Troy, et al.
Publicado: (2006)

Different Pathological Roles of Toll-Like Receptor 9 on Mucosal B Cells and Dendritic Cells in Murine IgA Nephropathy
por: Kajiyama, Tadahiro, et al.
Publicado: (2011)

A small peptide antagonist of the Fas receptor inhibits neuroinflammation and prevents axon degeneration and retinal ganglion cell death in an inducible mouse model of glaucoma
por: Krishnan, Anitha, et al.
Publicado: (2019)

Radioresistant cells initiate lymphocyte-dependent lung inflammation and IFNγ-dependent mortality in STING gain-of-function mice
por: Gao, Kevin MingJie, et al.
Publicado: (2022)

Chromatin Architecture as an Essential Determinant of Dendritic Cell Function
por: Boukhaled, Giselle M., et al.
Publicado: (2019)

Chromatin Landscape Underpinning Human Dendritic Cell Heterogeneity
por: Leylek, Rebecca, et al.
Publicado: (2020)

Toll‐like receptors matter: plasmacytoid dendritic cells in COVID‐19
por: Becker, Jennifer, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_gumbfu739lmmlq47i1sd7t1vt0