Thymic output generates a new and diverse TCR repertoire after autologous stem cell transplantation in multiple sclerosis patients

Clinical trials have indicated that autologous hematopoietic stem cell transplantation (HSCT) can persistently suppress inflammatory disease activity in a subset of patients with severe multiple sclerosis (MS), but the mechanism has remained unclear. To understand whether the beneficial effects on t...

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Detalles Bibliográficos
Autores principales: Muraro, Paolo A., Douek, Daniel C., Packer, Amy, Chung, Katherine, Guenaga, Francisco J., Cassiani-Ingoni, Riccardo, Campbell, Catherine, Memon, Sarfraz, Nagle, James W., Hakim, Frances T., Gress, Ronald E., McFarland, Henry F., Burt, Richard K., Martin, Roland
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212822/
https://www.ncbi.nlm.nih.gov/pubmed/15738052
http://dx.doi.org/10.1084/jem.20041679

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