Controlling inflammation: a fat chance?

The inflammatory response protects the body against infection and injury but can itself become deregulated with deleterious consequences to the host. It is now clear that several endogenous biochemical pathways activated during defense reactions can counterregulate inflammation. New experimental evi...

Descripción completa

Detalles Bibliográficos
Autores principales: Flower, Roderick J., Perretti, Mauro
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212824/
https://www.ncbi.nlm.nih.gov/pubmed/15753201
http://dx.doi.org/10.1084/jem.20050222
_version_ 1782148766620450816
author Flower, Roderick J.
Perretti, Mauro
author_facet Flower, Roderick J.
Perretti, Mauro
author_sort Flower, Roderick J.
collection PubMed
description The inflammatory response protects the body against infection and injury but can itself become deregulated with deleterious consequences to the host. It is now clear that several endogenous biochemical pathways activated during defense reactions can counterregulate inflammation. New experimental evidence adds resolvin E1 to this group of endogenous inhibitors and provides further rationale for the beneficial effects of dietary supplementation with fish oils. It also highlights an unexpected twist in the pharmacology of aspirin.
format Text
id pubmed-2212824
institution National Center for Biotechnology Information
language English
publishDate 2005
publisher The Rockefeller University Press
record_format MEDLINE/PubMed
spelling pubmed-22128242008-03-11 Controlling inflammation: a fat chance? Flower, Roderick J. Perretti, Mauro J Exp Med Commentary The inflammatory response protects the body against infection and injury but can itself become deregulated with deleterious consequences to the host. It is now clear that several endogenous biochemical pathways activated during defense reactions can counterregulate inflammation. New experimental evidence adds resolvin E1 to this group of endogenous inhibitors and provides further rationale for the beneficial effects of dietary supplementation with fish oils. It also highlights an unexpected twist in the pharmacology of aspirin. The Rockefeller University Press 2005-03-07 /pmc/articles/PMC2212824/ /pubmed/15753201 http://dx.doi.org/10.1084/jem.20050222 Text en Copyright © 2005, The Rockefeller University Press This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Commentary
Flower, Roderick J.
Perretti, Mauro
Controlling inflammation: a fat chance?
title Controlling inflammation: a fat chance?
title_full Controlling inflammation: a fat chance?
title_fullStr Controlling inflammation: a fat chance?
title_full_unstemmed Controlling inflammation: a fat chance?
title_short Controlling inflammation: a fat chance?
title_sort controlling inflammation: a fat chance?
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212824/
https://www.ncbi.nlm.nih.gov/pubmed/15753201
http://dx.doi.org/10.1084/jem.20050222
work_keys_str_mv AT flowerroderickj controllinginflammationafatchance
AT perrettimauro controllinginflammationafatchance

Ejemplares similares